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Notably, 13 genes and their corresponding proteins were upregulated in group H-IMF, including LCN2 (Lipocalin 2), MPO (Myeloperoxidase), CATHL4 (Cathelicidin 4), ACAN (Aggrecan), TTN (Titin), CATHL3 (Cathelicidin 3), CHAD (Chondroadherin), PGLYRP1 (Peptidoglycan Recognition Protein 1), AZU1 (Azurocidin 1), COL2A1 (Collagen Type II Alpha 1 Chain), PRG3 (Proteoglycan 3), and NGP (Neutrophilic Granule Protein)

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FMC and an additional batch of choline chloride were sourced from A2B Chem LLC (United State), whereas vancomycin was purchased from Millipore

Statistical analysis was performed using SPSS software (version 22